An Uncommon Descent blog buried in the Christmas rush drew attention to an article in that august scientific journal, Harper’s Magazine, by Alan Lightman. It is essentially an overview of multiverse theory in physics, but makes the point that acceptance of the multiverse hypothesis renders science’s quest for ultimate causes meaningless:
Dramatic developments in cosmological findings and thought have led some of the worlds premier physicists to propose that our universe is only one of an enormous number of universes with wildly varying properties, and that some of the most basic features of our particular universe are indeed mere accidentsa random throw of the cosmic dice. In which case, there is no hope of ever explaining our universes features in terms of fundamental causes and principles.